Structure of PDB 2e6v Chain B Binding Site BS02

Receptor Information
>2e6v Chain B (length=237) Species: 9615 (Canis lupus familiaris) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EHLKREHSLIKPYQGMPLWDFQGSTILTSQYVRLTPDERSKEGSIWNHQP
CFLKDWEMHVHFKVHGTNLHGDGIALWYTRDRLVPGPVFGSKDNFHGLAI
FLDTYPNDETTERVFPYISVMVNNGSLSYDHSKDGRWTELAGCTADFRNR
DHDTFLAVRYSRGRLTVMTDLEDKWKNCIDITGVRLPTGYYFGASAGTGD
LSDNHDIISMKLFQLMVEHTPDEENIDWTKIEPSVNF
Ligand information
Ligand IDMAN
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5+,6+/m1/s1
InChIKeyWQZGKKKJIJFFOK-PQMKYFCFSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C1C(C(C(C(O1)O)O)O)O)O
CACTVS 3.341OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
CACTVS 3.341OC[C@H]1O[C@H](O)[C@@H](O)[C@@H](O)[C@@H]1O
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@@H]([C@@H]([C@H](O1)O)O)O)O)O
ACDLabs 10.04OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namealpha-D-mannopyranose;
alpha-D-mannose;
D-mannose;
mannose
ChEMBLCHEMBL365590
DrugBank
ZINCZINC000003860903
PDB chain2e6v Chain G Residue 3 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2e6v Structural basis for recognition of high mannose type glycoproteins by mammalian transport lectin VIP36
Resolution2.5 Å
Binding residue
(original residue number in PDB)		D131 Y164 H190 G260 D261 L262
Binding residue
(residue number reindexed from 1)		D72 Y105 H131 G199 D200 L201
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:2e6v, PDBe:2e6v, PDBj:2e6v
PDBsum2e6v
PubMed17652092
UniProtP49256|LMAN2_CANLF Vesicular integral-membrane protein VIP36 (Gene Name=LMAN2)

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