Structure of PDB 2e52 Chain B Binding Site BS02

Receptor Information
>2e52 Chain B (length=298) Species: 71421 (Haemophilus influenzae Rd KW20) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KSALEKLLSLIENLTNQEFKQATNSLISFIYKLNRNEVIELVRSIGILPE
AIKPSSTQEKLFSKAGDIVLAKAFQLLNLNSKPLEQRGNAGDVIALSKEF
NYGLVADAKSFRLSRTAKNQKDFKVKALSEWREDKDYAVLTAPFFQYPTT
KSQIFKQSLDENVLLFSWEHLAILLQLDLEETNIFSFEQLWNFPKKQSKK
TSVSDAENNFMRDFNKYFMDLFKIDKDTLNQLLQKEINFIEERSLIEKEY
WKKQINIIKNFTREEAIEALLKDINMSSKIETIDSFIKGIKSNDRLYL
Ligand information
Receptor-Ligand Complex Structure
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PDB2e52 Structures of restriction endonuclease HindIII in complex with its cognate DNA and divalent cations
Resolution2.0 Å
Binding residue
(original residue number in PDB)		L49 E60 S64 R88 G89 N90 D93 S111 F112 R113 R116 T117 A118 D123 K125 W132
Binding residue
(residue number reindexed from 1)		L48 E59 S63 R87 G88 N89 D92 S110 F111 R112 R115 T116 A117 D122 K124 W131
Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function
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Biological Process
External links
PDB RCSB:2e52, PDBe:2e52, PDBj:2e52
PDBsum2e52
PubMed19966419
UniProtP43870|T2D3_HAEIN Type II restriction enzyme HindIII (Gene Name=hindIIIR)

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