Structure of PDB 2d3r Chain B Binding Site BS02

Receptor Information

>2d3r Chain B (length=236) Species: 83131 (Cratylia argentea)

ADTIVAVELDTYPNTDIGDPNYQHIGINIKSIRSKATTRWNVQDGKVGTA
HISYNSVAKRLSAIVSYPGGSSATVSYDVDLNNILPEWVRVGLSASTGLY
KETNTILSWSFTSKLKTNSTADAQSLHFTFNQFSQNPKDLILQGDASTDS
DGNLQLTRVSNGSPQSNSVGRALYYAPVHVWDKSAVVASFDATFTFLIKS
TDSDIADGIAFFIANTDSSIPHGSGGRLLGLFPDAN

Ligand information

• Ligand ID: MN
• InChI: InChI=1S/Mn/q+2
• InChIKey: WAEMQWOKJMHJLA-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mn+2]
  CACTVS 3.341: [Mn++]
• Formula: Mn
• Name: MANGANESE (II) ION
• DrugBank: DB06757
• PDB chain: 2d3r Chain B Residue 242

Receptor-Ligand Complex Structure

Structure summary

• PDB: 2d3r Crystal structures of Cratylia floribunda seed lectin at acidic and basic pHs. Insights into the structural basis of the pH-dependent dimer-tetramer transition.
• Resolution: 2.9 Å
• Binding residue (original residue number in PDB): E8 D10 D19 H24
• Binding residue (residue number reindexed from 1): E8 D10 D19 H24
• Annotation score: 4

Gene Ontology

Molecular Function

• GO:0005537 D-mannose binding
• GO:0030246 carbohydrate binding
• GO:0046872 metal ion binding
• GO:0090729 toxin activity

Biological Process

• GO:0008150 biological_process
• GO:0035821 modulation of process of another organism

Cellular Component

• GO:0005575 cellular_component

External links

• PDB: RCSB:2d3r, PDBe:2d3r, PDBj:2d3r
• PDBsum: 2d3r
• PubMed: 17251039
• UniProt: P81517|LECA_CRAAG Lectin alpha chain