Structure of PDB 2cnw Chain B Binding Site BS02

Receptor Information
>2cnw Chain B (length=290) Species: 271 (Thermus aquaticus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QLSARLQEAIGRLRGRGRITEEDLKATLREIRRALMDADVNLEVARDFVE
RVREEALGKQVLESLTPAEVILATVYEALKEALGGEARLPVLKDRNLWFL
VGLQGSGKTTTAAKLALYYKGKGRRPLLVAADTQRPAAREQLRLLGEKVG
VPVLEVMDGESPESIRRRVEEKARLEARDLILVDTAGRLQIDEPLMGELA
RLKEVLGPDEVLLVLDAMTGQEALSVARAFDEKVGVTGLVLTKLDGDARG
GAALSARHVTGKPIYFAGVSEKPEGLEPFYPERLAGRILG
Ligand information
Ligand IDALF
InChIInChI=1S/Al.4FH/h;4*1H/q+3;;;;/p-4
InChIKeyUYOMQIYKOOHAMK-UHFFFAOYSA-J
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		F[Al-](F)(F)F
FormulaAl F4
NameTETRAFLUOROALUMINATE ION
ChEMBL
DrugBankDB04444
ZINC
PDB chain2cnw Chain B Residue 1007 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2cnw Structure of a Gdp:Alf(4) Complex of the Srp Gtpases Ffh and Ftsy, and Identification of a Peripheral Nucleotide Interaction Site.
Resolution2.39 Å
Binding residue
(original residue number in PDB)		Q107 G108 K111 R138 G190
Binding residue
(residue number reindexed from 1)		Q104 G105 K108 R135 G187
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.5.4: signal-recognition-particle GTPase.
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
Cellular Component
GO:0048500 signal recognition particle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2cnw, PDBe:2cnw, PDBj:2cnw
PDBsum2cnw
PubMed16780874
UniProtO07347|SRP54_THEAQ Signal recognition particle protein (Gene Name=ffh)

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