Structure of PDB 2bs2 Chain B Binding Site BS02

Receptor Information
>2bs2 Chain B (length=239) Species: 844 (Wolinella succinogenes) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MGRMLTIRVFKYDPQSAVSKPHFQEYKIEEAPSMTIFIVLNMIRETYDPD
LNFDFVCRAGICGSCGMMINGRPSLACRTLTKDFEDGVITLLPLPAFKLI
KDLSVDTGNWFNGMSQRVESWIHAQKEHDISKLEERIEPEVAQEVFELDR
CIECGCCIAACGTKIMREDFVGAAGLNRVVRFMIDPHDERTDEDYYELIG
DDDGVFGCMTLLACHDVCPKNLPLQSKIAYLRRKMVSVN
Ligand information
Ligand IDF3S
InChIInChI=1S/3Fe.4S
InChIKeyFCXHZBQOKRZXKS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.385S1[Fe]S[Fe]2S[Fe]1S2
OpenEye OEToolkits 2.0.7S1[Fe]2S[Fe]3[S]2[Fe]1S3
FormulaFe3 S4
NameFE3-S4 CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain2bs2 Chain B Residue 1241 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2bs2 Evidence for Transmembrane Proton Transfer in a Dihaem-Containing Membrane Protein Complex.
Resolution1.78 Å
Binding residue
(original residue number in PDB)		C161 T163 F170 C208 M209 T210 L211 L212 C214
Binding residue
(residue number reindexed from 1)		C161 T163 F170 C208 M209 T210 L211 L212 C214
Annotation score1
Enzymatic activity
Enzyme Commision number 1.3.5.1: succinate dehydrogenase.
Gene Ontology
Molecular Function
GO:0009055 electron transfer activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0051536 iron-sulfur cluster binding
GO:0051537 2 iron, 2 sulfur cluster binding
GO:0051538 3 iron, 4 sulfur cluster binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0006099 tricarboxylic acid cycle
GO:0009060 aerobic respiration
GO:0022904 respiratory electron transport chain
Cellular Component
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2bs2, PDBe:2bs2, PDBj:2bs2
PDBsum2bs2
PubMed17024183
UniProtP17596|FRDB_WOLSU Fumarate reductase iron-sulfur subunit (Gene Name=frdB)

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