Structure of PDB 2bpe Chain B Binding Site BS02

Receptor Information
>2bpe Chain B (length=128) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QSCLPNWIMHGKSCYLFSFSGNSWYGSKRHCSQLGAHLLKIDNSKEFEFI
ESQTSSHRINAFWIGLSRNQSEGPWFWEDGSAFFPNSFQVRNAVPQESLL
HNCVWIHGSEVYNQICNTSSYSICEKEL
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2bpe Chain B Residue 1245 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2bpe Structure of the Fungal Beta-Glucan-Binding Immune Receptor Dectin-1: Implications for Function.
Resolution2.25 Å
Binding residue
(original residue number in PDB)		K156 D158 E162 E241
Binding residue
(residue number reindexed from 1)		K40 D42 E46 E125
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0001872 (1->3)-beta-D-glucan binding
Biological Process
GO:0071226 cellular response to molecule of fungal origin

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Molecular Function
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Biological Process
External links
PDB RCSB:2bpe, PDBe:2bpe, PDBj:2bpe
PDBsum2bpe
PubMed17473009
UniProtQ6QLQ4|CLC7A_MOUSE C-type lectin domain family 7 member A (Gene Name=Clec7a)

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