Structure of PDB 2b9s Chain B Binding Site BS02
Receptor Information
>2b9s Chain B (length=52) Species:
5661
(Leishmania donovani) [
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KAVSLGTSKINYIDPRIICSWAKAQDVPINKIFSATIQKKFPWAMNAENF
DF
Ligand information
>2b9s Chain E (length=22) [
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aaaaatttttctaagtcttttt
Receptor-Ligand Complex Structure
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PDB
2b9s
The Structure of the Transition State of the Heterodimeric Topoisomerase I of Leishmania donovani as a Vanadate Complex with Nicked DNA.
Resolution
2.27 Å
Binding residue
(original residue number in PDB)
S244 T246
Binding residue
(residue number reindexed from 1)
S34 T36
Enzymatic activity
Enzyme Commision number
5.99.1.2
: Transferred entry: 5.6.2.1.
Gene Ontology
Molecular Function
GO:0003677
DNA binding
GO:0003917
DNA topoisomerase type I (single strand cut, ATP-independent) activity
Biological Process
GO:0006265
DNA topological change
Cellular Component
GO:0005694
chromosome
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Molecular Function
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Cellular Component
External links
PDB
RCSB:2b9s
,
PDBe:2b9s
,
PDBj:2b9s
PDBsum
2b9s
PubMed
16487540
UniProt
Q8WQM6
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