Structure of PDB 2anv Chain B Binding Site BS02

Receptor Information

>2anv Chain B (length=146) Species: 10754 (Lederbergvirus P22)

MMQISSNGITRLKREEGERLKAYSDSRGIPTIGVGHTGKVDGNSVASGMT
ITAEKSSELLKEDLQWVEDAISSLVRVPLNQNQYDAMCSLIFNIGKSAFA
GSTVLRQLNLKNYQAAADAFLLWKKAGKDPDILLPRRRRERALFLS

Ligand information

• Ligand ID: IOD
• InChI: InChI=1S/HI/h1H/p-1
• InChIKey: XMBWDFGMSWQBCA-UHFFFAOYSA-M
• SMILES:
  ACDLabs 10.04
  CACTVS 3.341
  OpenEye OEToolkits 1.5.0: [I-]
• Formula: I
• Name: IODIDE ION
• DrugBank: DB12754
• PDB chain: 2anv Chain B Residue 2981

Receptor-Ligand Complex Structure

Structure summary

• PDB: 2anv Extension to 2268 atoms of direct methods in the ab initio determination of the unknown structure of bacteriophage P22 lysozyme.
• Resolution: 1.04 Å
• Binding residue (original residue number in PDB): Y23 S24 S47
• Binding residue (residue number reindexed from 1): Y23 S24 S47
• Annotation score: 3

Enzymatic activity

• Enzyme Commision number: 3.2.1.17: lysozyme.

Gene Ontology

Molecular Function

• GO:0003796 lysozyme activity
• GO:0016798 hydrolase activity, acting on glycosyl bonds

Biological Process

• GO:0009253 peptidoglycan catabolic process
• GO:0016998 cell wall macromolecule catabolic process
• GO:0031640 killing of cells of another organism
• GO:0042742 defense response to bacterium
• GO:0044659 viral release from host cell by cytolysis

Cellular Component

• GO:0030430 host cell cytoplasm

External links

• PDB: RCSB:2anv, PDBe:2anv, PDBj:2anv
• PDBsum: 2anv
• PubMed: 16421448
• UniProt: P09963|ENLYS_BPP22 Endolysin (Gene Name=19)