Structure of PDB 1z1b Chain B Binding Site BS02

Receptor Information
>1z1b Chain B (length=350) Species: 10710 (Lambdavirus lambda) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HERRDLPPNLYIRNNGYYCYRDPRTGKEFGLGRDRRIAITEAIQANIELF
SGHKHKPLTARINSDNSVTLHSWLDRYEKILASRGIKQKTLINYMSKIKA
IRRGLPDAPLEDITTKEIAAMLNGYIDEGKAASAKLIRSTLSDAFREAIA
EGHITTNHVAATRAAKSKVRRSRLTADEYLKIYQAAESSPCWLRLAMELA
VVTGQRVGDLCEMKWSDIVDGYLYVEQSKTGVKIAIPTALHIDALGISMK
ETLDKCKEILGGETIIASTRREPLSSGTVSRYFMRARKASGLSFEGDPPT
FHELRSLSARLYEKQISDKFAQHLLGHKSDTMASQYRDDRGREWDKIEIK
Ligand information
Receptor-Ligand Complex Structure
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PDB1z1b A structural basis for allosteric control of DNA recombination by lambda integrase.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		K93 K95 T96 N99 Y100 G214 S234 K235 S286 R287 M290 R293 T306 F307 H308
Binding residue
(residue number reindexed from 1)		K87 K89 T90 N93 Y94 G208 S228 K229 S280 R281 M284 R287 T300 F301 H302
Enzymatic activity
Enzyme Commision number 2.7.7.-
3.1.-.-
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0008907 integrase activity
GO:0016740 transferase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006310 DNA recombination
GO:0015074 DNA integration
GO:0032359 provirus excision
GO:0044826 viral genome integration into host DNA
GO:0046718 symbiont entry into host cell
GO:0075713 establishment of integrated proviral latency

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Molecular Function
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Biological Process
External links
PDB RCSB:1z1b, PDBe:1z1b, PDBj:1z1b
PDBsum1z1b
PubMed15973401
UniProtP03700|VINT_LAMBD Integrase (Gene Name=int)

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