Structure of PDB 1y6h Chain B Binding Site BS02

Receptor Information
>1y6h Chain B (length=177) Species: 173 (Leptospira interrogans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SVRKILRMGDPILRKISEPVTEDEIQTKEFKKLIRDMFDTMRHAEGVGLA
APQIGILKQIVVVGSEDNERYPGTPDVPERIILNPVITPLTKDTSGFWEG
CLSVPGMRGYVERPNQIRMQWMDEKGNQFDETIDGYKAIVYQHECDHLQG
ILYVDRLKDTKLFGFNETLDSSHNVLD
Ligand information
Ligand IDGLY
InChIInChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
InChIKeyDHMQDGOQFOQNFH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C(=O)O)N
CACTVS 3.341NCC(O)=O
ACDLabs 10.04O=C(O)CN
FormulaC2 H5 N O2
NameGLYCINE
ChEMBLCHEMBL773
DrugBankDB00145
ZINCZINC000004658552
PDB chain1y6h Chain B Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1y6h Unique structural characteristics of peptide deformylase from pathogenic bacterium Leptospira interrogans
Resolution2.2 Å
Binding residue
(original residue number in PDB)		Y71 E99 H143
Binding residue
(residue number reindexed from 1)		Y71 E99 H143
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) G48 Q53 C101 L102 H143 E144 H147
Catalytic site (residue number reindexed from 1) G48 Q53 C101 L102 H143 E144 H147
Enzyme Commision number 3.5.1.88: peptide deformylase.
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0042586 peptide deformylase activity
GO:0046872 metal ion binding
Biological Process
GO:0006412 translation
GO:0043686 co-translational protein modification

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Molecular Function
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Biological Process
External links
PDB RCSB:1y6h, PDBe:1y6h, PDBj:1y6h
PDBsum1y6h
PubMed15123432
UniProtQ93LE9|DEF_LEPIN Peptide deformylase (Gene Name=def)

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