Structure of PDB 1x11 Chain B Binding Site BS02
Receptor Information
>1x11 Chain B (length=122) Species:
9606
(Homo sapiens) [
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IIFAANYLGSTQLLVRMMQAQEAVSRIKMAQKLAKSMTEVDLFILTQRIK
VLNADTQETMMDHPLRTISYIADIGNIVVLMARYKMICHVFESEDAQLIA
QSIGQAFSVAYQEFLRANGINP
Ligand information
>1x11 Chain D (length=13) Species:
9606
(Homo sapiens) [
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QNGYENPTYKFFE
Receptor-Ligand Complex Structure
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PDB
1x11
Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain.
Resolution
2.5 Å
Binding residue
(original residue number in PDB)
M354 L413 R414 T415 I416 S417 Y418 I419 A420 D421 G423 R431 Q469 F479 Y483 F486
Binding residue
(residue number reindexed from 1)
M17 L65 R66 T67 I68 S69 Y70 I71 A72 D73 G75 R83 Q97 F107 Y111 F114
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:1x11
,
PDBe:1x11
,
PDBj:1x11
PDBsum
1x11
PubMed
9321393
UniProt
Q02410
|APBA1_HUMAN Amyloid-beta A4 precursor protein-binding family A member 1 (Gene Name=APBA1)
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