Structure of PDB 1vkx Chain B Binding Site BS02
Receptor Information
>1vkx Chain B (length=312) Species:
10090
(Mus musculus) [
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GPYLQILEQPKQRGFRFRYVCEGPSHGGLPGASSEKNKKSYPQVKICNYV
GPAKVIVQLVTNGKNIHLHAHSLVGKHCEDGVCTVTAGPKDMVVGFANLG
ILHVTKKKVFETLEARMTEACIRGYNPGLLVHSDLAYLQAEGGGDRQLTD
REKEIIRQAAVQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAIY
DSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEEN
GGVWEGFGDFSPTDVHRQFAIVFKTPKYKDVNITKPASVFVQLRRKSDLE
TSEPKPFLYYPE
Ligand information
>1vkx Chain D (length=12) [
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aggaaagtcccc
Receptor-Ligand Complex Structure
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PDB
1vkx
Crystal structure of p50/p65 heterodimer of transcription factor NF-kappaB bound to DNA.
Resolution
2.9 Å
Binding residue
(original residue number in PDB)
Y357 C359 H364 T443 K444 K541 R605 Q606
Binding residue
(residue number reindexed from 1)
Y19 C21 H26 T105 K106 K203 R267 Q268
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003677
DNA binding
GO:0003700
DNA-binding transcription factor activity
Biological Process
GO:0006355
regulation of DNA-templated transcription
Cellular Component
GO:0005737
cytoplasm
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:1vkx
,
PDBe:1vkx
,
PDBj:1vkx
PDBsum
1vkx
PubMed
9450761
UniProt
P25799
|NFKB1_MOUSE Nuclear factor NF-kappa-B p105 subunit (Gene Name=Nfkb1)
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