Structure of PDB 1u2w Chain B Binding Site BS02

Receptor Information
>1u2w Chain B (length=107) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GYDEEKVNRIQGDLQTVDISGVSQILKAIADENRAKITYALCQDEELCVC
DIANILGVTIANASHHLRTLYKQGVVNFRKEGKLALYSLGDEHIRQIMMI
ALAHKKE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1u2w Chain B Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1u2w Crystal structure of the Staphylococcus aureus pI258 CadC Cd(II)/Pb(II)/Zn(II)-responsive repressor
Resolution1.9 Å
Binding residue
(original residue number in PDB)		D101 H103
Binding residue
(residue number reindexed from 1)		D91 H93
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0046872 metal ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0046686 response to cadmium ion

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Molecular Function
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Biological Process
External links
PDB RCSB:1u2w, PDBe:1u2w, PDBj:1u2w
PDBsum1u2w
PubMed15937183
UniProtP20047|CADC_STAAU Cadmium resistance transcriptional regulatory protein CadC (Gene Name=cadC)

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