Structure of PDB 1ty4 Chain B Binding Site BS02
Receptor Information
>1ty4 Chain B (length=166) Species:
6239
(Caenorhabditis elegans) [
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NDWEEPRLDIEGFVVDYFTHRIRQNGMEWFGAPGLPCGVQPEHEMMRVMG
TIFEKKHAENFETFCEQLLAVPRISFSPYQDVVRTVGNAQTDQCPMSYGR
LIGLISFGGFVAAKMMESVELQGQVRNLFVYTSLFIKTRIRNNWKEHNRS
WDDFMTLGKQMKEDYE
Ligand information
>1ty4 Chain D (length=27) Species:
6239
(Caenorhabditis elegans) [
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SSIGYEIGSKLAAMCDDFDAQMMSYSA
Receptor-Ligand Complex Structure
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PDB
1ty4
Structural, Biochemical, and Functional Analyses of CED-9 Recognition by the Proapoptotic Proteins EGL-1 and CED-4
Resolution
2.2 Å
Binding residue
(original residue number in PDB)
F123 K126 H127 F134 Q137 D151 V152 T155 V156 Q163 S167 Y168 G169 R170 I172 Q230 M231 D234 Y235
Binding residue
(residue number reindexed from 1)
F53 K56 H57 F64 Q67 D81 V82 T85 V86 Q93 S97 Y98 G99 R100 I102 Q160 M161 D164 Y165
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Biological Process
GO:0042981
regulation of apoptotic process
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Biological Process
External links
PDB
RCSB:1ty4
,
PDBe:1ty4
,
PDBj:1ty4
PDBsum
1ty4
PubMed
15383288
UniProt
P41958
|CED9_CAEEL Apoptosis regulator ced-9 (Gene Name=ced-9)
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