Structure of PDB 1sum Chain B Binding Site BS02

Receptor Information

>1sum Chain B (length=225) Species: 2336 (Thermotoga maritima) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

NRLLNEKVEEFKKGVLKAGWFIEKMFRNSISSLVERNESLAREVIADEEV
VDQMEVEIQEKAMEVLGLFSPIGKPLLTVTAGIRVAELIENIADKCHDIA
KNVLELMEEPPLKPLEDIPAMANQTSEMLKFALRMFADVNVEKSFEVCRM
DSKVDDLYEKVREELLLYMMESPKYVKRALLLLEIAGNIEIIADYATNIV
EVSVYMVQGEAYKCYHDELLLFKKS

Ligand information

Ligand ID

InChI

InChI=1S/Fe/q+3

InChIKey

VTLYFUHAOXGGBS-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 CACTVS 3.341 OpenEye OEToolkits 1.5.0	[Fe+3]

Formula

Name

FE (III) ION

PDB chain

1sum Chain B Residue 237 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	1sum Crystal structure of a PhoU protein homologue: a new class of metalloprotein containing multinuclear iron clusters.
Resolution	2.0 Å
Binding residue (original residue number in PDB)	E49 D53 E91 D95
Binding residue (residue number reindexed from 1)	E48 D52 E90 D94
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0042803	protein homodimerization activity

	Biological Process
GO:0006817	phosphate ion transport
GO:0030643	intracellular phosphate ion homeostasis
GO:0045936	negative regulation of phosphate metabolic process
GO:2000186	negative regulation of phosphate transmembrane transport

	Cellular Component
GO:0005737	cytoplasm

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Cellular Component

External links

PDB	RCSB:1sum, PDBe:1sum, PDBj:1sum
PDBsum	1sum
PubMed	15716271
UniProt	Q9X256\|PHOU2_THEMA Phosphate-specific transport system accessory protein PhoU homolog 2 (Gene Name=phoU2)

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