Structure of PDB 1qmg Chain B Binding Site BS02

Receptor Information
>1qmg Chain B (length=510) Species: 3562 (Spinacia oleracea) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FDFDSSVFKKEKVTLSGHDEYIVRGGRNLFPLLPDAFKGIKQIGVIGWGS
QAPAQAQNLKDSLTEAKSDVVVKIGLRKGSNSFAEARAAGFSEENGTLGD
MWETISGSDLVLLLISDSAQADNYEKVFSHMKPNSILGLSHGFLLGHLQS
LGQDFPKNISVIAVCPKGMGPSVRRLYVQGKEVNGAGINSSFAVHQDVDG
RATDVALGWSIALGSPFTFATTLEQEYKSDIFGERGILLGAVHGIVECLF
RRYTESGMSEDLAYKNTVECITGVISKTISTKGMLALYNSLSEEGKKDFQ
AAYSASYYPSMDILYECYEDVASGSEIRSVVLAGRRFYEKEGLPAFPMGK
IDQTRMWKVGEKVRSVRPAGDLGPLYPFTAGVYVALMMAQIEILRKKGHS
YSEIINESVIEAVDSLNPFMHARGVSFMVDNCSTTARLGSRKWAPRFDYI
LSQQALVAVDNGAPINQDLISNFLSDPVHEAIGVCAQLRPSVDISVTADA
DFVRPELRQA
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain1qmg Chain B Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1qmg Structure of Spinach Acetohydroxyacid Isomeroreductase Complexed with its Product of Reaction Dihydroxy-Methylvalerate, Manganese and Adp-Ribose
Resolution1.6 Å
Binding residue
(original residue number in PDB)		D315 E319
Binding residue
(residue number reindexed from 1)		D230 E234
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) K252 D315 E319
Catalytic site (residue number reindexed from 1) K167 D230 E234
Enzyme Commision number 1.1.1.86: ketol-acid reductoisomerase (NADP(+)).
Gene Ontology
Molecular Function
GO:0004455 ketol-acid reductoisomerase activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0009082 branched-chain amino acid biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:1qmg, PDBe:1qmg, PDBj:1qmg
PDBsum1qmg
PubMed10739911
UniProtQ01292|ILV5_SPIOL Ketol-acid reductoisomerase, chloroplastic (Gene Name=AHRI)

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