Structure of PDB 1qd1 Chain B Binding Site BS02

Receptor Information
>1qd1 Chain B (length=325) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SQLVECVPNFSEGKNQEVIDAISRAVAQTPGCVLLDVDSGPSTNRTVYTF
VGRPEDVVEGALNAARAAYQLIDMSRHHGEHPRMGALDVCPFIPVRGVTM
DECVRCAQAFGQRLAEELGVPVYLYGEAARTAGRQSLPALRAGEYEALPE
KLKQAEWAPDFGPSAFVPSWGATVAGARKFLLAFNINLLSTREQAHRIAL
DLREQGRGKDQPGRLKKVQAIGWYLDEKNLAQVSTNLLDFEVTGLHTVFE
ETCREAQELSLPVVGSQLVGLVPLKALLDAAAFYCEKENLFLLQDEHRIR
LVVNRLGLDSLAPFKPKERIIEYLV
Ligand information
Ligand IDGOL
InChIInChI=1S/C3H8O3/c4-1-3(6)2-5/h3-6H,1-2H2
InChIKeyPEDCQBHIVMGVHV-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.0C(C(CO)O)O
ACDLabs 12.01
CACTVS 3.370		OCC(O)CO
FormulaC3 H8 O3
NameGLYCEROL;
GLYCERIN;
PROPANE-1,2,3-TRIOL
ChEMBLCHEMBL692
DrugBankDB09462
ZINCZINC000000895048
PDB chain1qd1 Chain B Residue 2480 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1qd1 The crystal structure of the formiminotransferase domain of formiminotransferase-cyclodeaminase: implications for substrate channeling in a bifunctional enzyme.
Resolution1.7 Å
Binding residue
(original residue number in PDB)		H2082 R2142 S2235 T2236
Binding residue
(residue number reindexed from 1)		H81 R141 S234 T235
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) H2082
Catalytic site (residue number reindexed from 1) H81
Enzyme Commision number 2.1.2.5: glutamate formimidoyltransferase.
4.3.1.4: formimidoyltetrahydrofolate cyclodeaminase.
Gene Ontology
Molecular Function
GO:0005542 folic acid binding
GO:0016740 transferase activity

View graph for
Molecular Function
External links
PDB RCSB:1qd1, PDBe:1qd1, PDBj:1qd1
PDBsum1qd1
PubMed10673422
UniProtP53603|FTCD_PIG Formimidoyltransferase-cyclodeaminase (Gene Name=FTCD)

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