Structure of PDB 1pvp Chain B Binding Site BS02

Receptor Information
>1pvp Chain B (length=318) Species: 10678 (Punavirus P1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TSDEVRKNLMDMFRDRQAFSEHTWKMLLSVCRSWAAWCKLNNRKWFPAEP
EDVRDYLLYLQARGLAVKTIQQHLGQLNMLHRRSGLPRPSDSNAVSLVMR
RIRKENVDAGERAKQALAFERTDFDQVRSLMENSDRCQDIRNLAFLGIAY
NTLLRAAEIARIRVKDISRTDGGRMLIHIGRTKTLVSTAGVEKALSLGVT
KLVERWISVSGVADDPNNYLFCRVRKNGVAAPSATSQLSLSALHGIFGAT
HRLIYGAKDDSGQRYLAWSGHSARVGAARDMARAGVSIPEIMQAGGWTNV
NIVMNYIRTGAMVRLLED
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1pvp A specificity switch in selected cre recombinase variants is mediated by macromolecular plasticity and water.
Resolution2.35 Å
Binding residue
(original residue number in PDB)
S38 H40 T41 Q90 M97 R106 R121 A175 K201 R243 N245 H262 R282 Y283 S287 G288 H289
Binding residue
(residue number reindexed from 1)
S20 H22 T23 Q72 M79 R88 R103 A157 K183 R225 N227 H244 R264 Y265 S269 G270 H271
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006310 DNA recombination
GO:0015074 DNA integration

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:1pvp, PDBe:1pvp, PDBj:1pvp
PDBsum1pvp
PubMed14652076
UniProtP06956|RECR_BPP1 Recombinase cre (Gene Name=cre)

[Back to BioLiP]