Structure of PDB 1o6p Chain B Binding Site BS02

Receptor Information
>1o6p Chain B (length=440) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MELITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVLANPGNS
QVARVAAGLQIKNSLTSKDPDIKAQYQQRWLAIDANARREVKNYVLHTLG
TETYRPSSASQCVAGIACAEIPVNQWPELIPQLVANVTNPNSTEHMKEST
LEAIGYICQDIDPEQLQDKSNEILTAIIQGMRKEEPSNNVKLAATNALLN
SLEFTKANFDKESERHFIMQVVCEATQCPDTRVRVAALQNLVKIMSLYYQ
YMETYMGPALFAITIEAMKSDIDEVALQGIEFWSNVCDEEMDLAIEASEA
AEQGRPPEHTSKFYAKGALQYLVPILTQTLTKQDENDDDDDWNPCKAAGV
CLMLLATCCEDDIVPHVLPFIKEHIKNPDWRYRDAAVMAFGCILEGPEPS
QLKPLVIQAMPTLIELMKDPSVVVRDTAAWTVGRICELLP
Ligand information
Receptor-Ligand Complex Structure
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PDB1o6p Glfg and Fxfg Nucleoporins Bind to Overlapping Sites on Importin-Beta
Resolution2.8 Å
Binding residue
(original residue number in PDB)		N171 E214
Binding residue
(residue number reindexed from 1)		N171 E214
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0031267 small GTPase binding
Biological Process
GO:0006606 protein import into nucleus
GO:0006886 intracellular protein transport

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Molecular Function
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Biological Process
External links
PDB RCSB:1o6p, PDBe:1o6p, PDBj:1o6p
PDBsum1o6p
PubMed12372823
UniProtQ14974|IMB1_HUMAN Importin subunit beta-1 (Gene Name=KPNB1)

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