Structure of PDB 1nne Chain B Binding Site BS02

Receptor Information
>1nne Chain B (length=759) Species: 271 (Thermus aquaticus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MEGMLKGEGPGPLPPLLQQYVELRDQYPDYLLLFQVGDFYECFGEDAERL
ARALGLVLTHKTSKDFTTPMAGIPLRAFEAYAERLLKMGFRLAVADQVEP
LVRREVTQLLTPGTLLQESLLPREANYLAAIATGDGWGLAFLDVSTGEFK
GTVLKSKSALYDELFRHRPAEVLLAPELLENGAFLDEFRKRFPVMLSEAP
FEPEGEGPLALRRARGALLAYAQRTQGGALSLQPFRFYDPGAFMRLPEAT
LRALEVFEPLRGQDTLFSVLDETRTAPGRRLLQSWLRHPLLDRGPLEARL
DRVEGFVREGALREGVRRLLYRLADLERLATRLELGRASPKDLGALRRSL
QILPELRALLGEEVGLPDLSPLKEELEAALVEDPPLKVSEGGLIREGYDP
DLDALRAAHREGVAYFLELEERERERTGIPTLKVGYNAVFGYYLEVTRPY
YERVPKEYRPVQTLKDRQRYTLPEMKEKEREVYRLEALIRRREEEVFLEV
RERAKRQAEALREAARILAELDVYAALAEVAVRYGYVRPRFGDRLQIRAG
RHPVVERRTEFVPNDLEMAHELVLITGPNMAGKSTFLRQTALIALLAQVG
SFVPAEEAHLPLFDGIYTRIGASDDLAGGKSTFMVEMEEVALILKEATEN
SLVLLDEVGRGTSSLDGVAIATAVAEALHERRAYTLFATHYFELTALGLP
RLKNLHVAAREEAGGLVFYHQVLPGPASKSYGVEVAAMAGLPKEVVARAR
ALLQAMAAR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1nne Crystal structure and biochemical analysis of the MutS-ADP-Beryllium Fluoride complex suggests a conserved mechanism for ATP interactions in mismatch repair
Resolution3.11 Å
Binding residue
(original residue number in PDB)		P1015 L1016 K1064 N1443 L1470 K1471 R1475
Binding residue
(residue number reindexed from 1)		P15 L16 K64 N437 L464 K465 R469
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003684 damaged DNA binding
GO:0003690 double-stranded DNA binding
GO:0005524 ATP binding
GO:0030983 mismatched DNA binding
GO:0140664 ATP-dependent DNA damage sensor activity
Biological Process
GO:0006281 DNA repair
GO:0006298 mismatch repair

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Molecular Function
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Biological Process
External links
PDB RCSB:1nne, PDBe:1nne, PDBj:1nne
PDBsum1nne
PubMed12582174
UniProtQ56215|MUTS_THEAQ DNA mismatch repair protein MutS (Gene Name=mutS)

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