Structure of PDB 1mhw Chain B Binding Site BS02

Receptor Information
>1mhw Chain B (length=174) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSE
QNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKY
NPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGI
YFEPDCSSEDMDHGVLVVGYGFES
Ligand information
Receptor-Ligand Complex Structure
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PDB1mhw Design of non-covalent inhibitors of human cathepsin L. From the 96-residue proregion to optimized tripeptides
Resolution1.9 Å
Binding residue
(original residue number in PDB)		Q21 E141 F145
Binding residue
(residue number reindexed from 1)		Q21 E141 F145
Enzymatic activity
Enzyme Commision number 3.4.22.15: cathepsin L.
Gene Ontology
Molecular Function
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1mhw, PDBe:1mhw, PDBj:1mhw
PDBsum1mhw
PubMed12431059
UniProtP07711|CATL1_HUMAN Procathepsin L (Gene Name=CTSL)

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