Structure of PDB 1mdm Chain B Binding Site BS02

Receptor Information
>1mdm Chain B (length=129) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RDRADLNKDKPVIPAAALAGYTGSGPIQLWQFLLELLTDKSCQSFISWTG
DGWEFKLSDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGK
RYVYRFVCDLQSLLGYTPEELHAMLDVKP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1mdm STRUCTURAL ANALYSIS OF THE AUTOINHIBITION OF ETS-1 AND ITS ROLE IN PROTEIN PARTNERSHIPS
Resolution2.8 Å
Binding residue
(original residue number in PDB)		Q336 L337 W375 K379 M384 K388 R391 Y396
Binding residue
(residue number reindexed from 1)		Q28 L29 W67 K71 M76 K80 R83 Y88
Binding affinityPDBbind-CN: Kd=35pM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II

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Molecular Function
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Biological Process
External links
PDB RCSB:1mdm, PDBe:1mdm, PDBj:1mdm
PDBsum1mdm
PubMed12221090
UniProtP27577|ETS1_MOUSE Protein C-ets-1 (Gene Name=Ets1)

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