Structure of PDB 1l7n Chain B Binding Site BS02

Receptor Information
>1l7n Chain B (length=210) Species: 2190 (Methanocaldococcus jannaschii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EKKKKLILFDFDSTLVNNETIDEIAREAGVEEEVKKITKEAMEGKLNFEQ
SLRKRVSLLKDLPIEKVEKAIKRITPTEGAEETIKELKNRGYVVAVVSGG
FDIAVNKIKEKLGLDYAFANRLIVKDGKLTGDVEGEVLKENAKGEILEKI
AKIEGINLEDTVAVGDGANDISMFKKAGLKIAFCAKPILKEKADICIEKR
DLREILKYIK
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain1l7n Chain B Residue 721 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1l7n Structural characterization of the reaction pathway in phosphoserine phosphatase: crystallographic "snapshots" of intermediate states.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		D511 D513 D667
Binding residue
(residue number reindexed from 1)		D10 D12 D166
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) D511 F512 D513 G600 K644 D671
Catalytic site (residue number reindexed from 1) D10 F11 D12 G99 K143 D170
Enzyme Commision number 3.1.3.3: phosphoserine phosphatase.
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0016787 hydrolase activity
GO:0036424 L-phosphoserine phosphatase activity
GO:0046872 metal ion binding
Biological Process
GO:0006564 L-serine biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1l7n, PDBe:1l7n, PDBj:1l7n
PDBsum1l7n
PubMed12051918
UniProtQ58989|SERB_METJA Phosphoserine phosphatase (Gene Name=MJ1594)

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