Structure of PDB 1kgz Chain B Binding Site BS02

Receptor Information

>1kgz Chain B (length=330) Species: 554 (Pectobacterium carotovorum)

THQPILEKLFKSQSMTQEESHQLFAAIVRGELEDSQLAAALISMKMRGER
PEEIAGAASALLADAQPFPRPDYDFADIVGTGGDGTNSINISTASAFVAA
SCGAKVAKHGNRSVLAGSCDLLQAFGIRLDMSAEDSRQALDDLNVCFLFA
PQYHTGFRHAMPVRQQLKTRTIFNVLGPLINPARPPKALIGVYSPELVLP
IAQALKVLGYKNAAVVHGGGMDEVAIHTPTQVAELNNGEIESYQLSPQDF
GLQSYSLNALQGGTPEENRDILARLLQGKGDAAHARQVAANVALLLKLFG
QDNLRHNAQLALETIRSGTAFERVTALAAR

Ligand information

• Ligand ID: MN
• InChI: InChI=1S/Mn/q+2
• InChIKey: WAEMQWOKJMHJLA-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mn+2]
  CACTVS 3.341: [Mn++]
• Formula: Mn
• Name: MANGANESE (II) ION
• DrugBank: DB06757
• PDB chain: 1kgz Chain B Residue 501

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1kgz The Crystal Structure of Anthranilate Phosphoribosyltransferase from the Enterobacterium Pectobacterium carotovorum
• Resolution: 2.4 Å
• Binding residue (original residue number in PDB): D236 E237
• Binding residue (residue number reindexed from 1): D222 E223
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 2.4.2.18: anthranilate phosphoribosyltransferase.

Gene Ontology

Molecular Function

• GO:0000287 magnesium ion binding
• GO:0004048 anthranilate phosphoribosyltransferase activity
• GO:0016757 glycosyltransferase activity
• GO:0016763 pentosyltransferase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0000162 tryptophan biosynthetic process

Cellular Component

• GO:0005829 cytosol

External links

• PDB: RCSB:1kgz, PDBe:1kgz, PDBj:1kgz
• PDBsum: 1kgz
• PubMed: 12123839
• UniProt: Q8VP84