Structure of PDB 1k7h Chain B Binding Site BS02

Receptor Information
>1k7h Chain B (length=476) Species: 6703 (Pandalus borealis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EEDKAYWNKDAQDALDKQLGIKLREKQAKNVIFFLGDGMSLSTVTAARIY
KGGLTGKFEREKISWEEFDFAALSKTYNTDKQVTDSAASATAYLTGVKTN
QGVIGLDANTVRTNCSYQLDESLFTYSIAHWFQEAGRSTGVVTSTRVTHA
TPAGTYAHVADRDWENDSDVVHDREDPEICDDIAEQLVFREPGKNFKVIM
GGGRRGFFPEEALDIEDGIPGEREDGKHLITDWLDDKASQGATASYVWNR
DDLLAVDIANTDYLMGLFSYTHLDTVLTRDAEMDPTLPEMTKVAIEMLTK
DENGFFLLVEGGRIDHMHHANQIRQSLAETLDMEEAVSMALSMTDPEETI
ILVTADHGHTLTITGYADRNTDILDFAGISDLDDRRYTILDYGSGPGYHI
TEDGKRYEPTEEDLKDINFRYASAAPKHSATHDGTDVGIWVNGPFAHLFT
GVYEENYIPHALAYAACVGTGRTFCD
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1k7h Chain B Residue 478 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1k7h The 1.9 A Crystal Structure of Heat-Labile Shrimp Alkaline Phosphatase
Resolution1.92 Å
Binding residue
(original residue number in PDB)		D37 S86 D356 H357
Binding residue
(residue number reindexed from 1)		D37 S86 D356 H357
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) D37 S86 H149 T151 R162 E310 D315 H316 H319 D356 H357 H432
Catalytic site (residue number reindexed from 1) D37 S86 H149 T151 R162 E310 D315 H316 H319 D356 H357 H432
Enzyme Commision number 3.1.3.1: alkaline phosphatase.
Gene Ontology
Molecular Function
GO:0004035 alkaline phosphatase activity
GO:0016787 hydrolase activity
GO:0016791 phosphatase activity
GO:0046872 metal ion binding
Biological Process
GO:0016311 dephosphorylation
Cellular Component
GO:0098552 side of membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1k7h, PDBe:1k7h, PDBj:1k7h
PDBsum1k7h
PubMed12083516
UniProtQ9BHT8

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