Structure of PDB 1k78 Chain B Binding Site BS02

Receptor Information
>1k78 Chain B (length=102) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWGKRKNKPKM
NYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHAMLD
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Ligand information
Receptor-Ligand Complex Structure
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PDB1k78 Structural studies of Ets-1/Pax5 complex formation on DNA.
Resolution2.25 Å
Binding residue
(original residue number in PDB)
Q336 L337 W375 K379 K388 R391 Y396
Binding residue
(residue number reindexed from 1)
Q2 L3 W41 K45 K54 R57 Y62
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II

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Molecular Function

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Biological Process
External links
PDB RCSB:1k78, PDBe:1k78, PDBj:1k78
PDBsum1k78
PubMed11779502
UniProtP27577|ETS1_MOUSE Protein C-ets-1 (Gene Name=Ets1)

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