Structure of PDB 1jca Chain B Binding Site BS02

Receptor Information
>1jca Chain B (length=30) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FVNQHLCGSHLVEALYLVCGERGFFYTPKT
Ligand information
>1jca Chain D (length=29) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
VNQHLCGSHLVEALYLVCGERGFFYTPKT
Receptor-Ligand Complex Structure
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PDB1jca Non-standard insulin design: structure-activity relationships at the periphery of the insulin receptor.
Resolution2.5 Å
Binding residue
(original residue number in PDB)
S9 V12 E13 Y16 G23 F24 F25 Y26 P28
Binding residue
(residue number reindexed from 1)
S9 V12 E13 Y16 G23 F24 F25 Y26 P28
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function

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Cellular Component
External links
PDB RCSB:1jca, PDBe:1jca, PDBj:1jca
PDBsum1jca
PubMed11779231
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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