Structure of PDB 1ii7 Chain B Binding Site BS02

Receptor Information
>1ii7 Chain B (length=332) Species: 2261 (Pyrococcus furiosus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKFAHLADIHLGYEQFHKPQREEEFAEAFKNALEIAVQENVDFILIAGDL
FHSSRPSPGTLKKAIALLQIPKEHSIPVFAIEGNHDRTQRGPSVLNLLED
FGLVYVIGMRKEKVENEYLTSERLGNGEYLVKGVYKDLEIHGMKYMSSAW
FEANKEILKRLFRPTDNAILMLHQGVREVSEARGEDYFEIGLGDLPEGYL
YYALGHIHKRYETSYSGSPVVYPGSLERWDFGDYEVRYEWDGIKFKERYG
VNKGFYIVEDFKPRFVEIKVRPFIDVKIKGSEEEIRKAIKRLIPLIPKNA
YVRLNIGWRKPFDLTEIKELLNVEYLKIDTWR
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain1ii7 Chain B Residue 406 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1ii7 Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		D8 H10 D49 H208
Binding residue
(residue number reindexed from 1)		D8 H10 D49 H208
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
Biological Process
GO:0000729 DNA double-strand break processing
GO:0006302 double-strand break repair

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Molecular Function
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Biological Process
External links
PDB RCSB:1ii7, PDBe:1ii7, PDBj:1ii7
PDBsum1ii7
PubMed11371344
UniProtQ8U1N9|MRE11_PYRFU DNA double-strand break repair protein Mre11 (Gene Name=mre11)

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