Structure of PDB 1i5k Chain B Binding Site BS02

Receptor Information
>1i5k Chain B (length=80) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EECMHGSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKN
YCRNPDRDLRPWCFTTDPNKRWEYCDIPRC
Ligand information
>1i5k Chain D (length=26) Species: 1314 (Streptococcus pyogenes) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
EKLTADAELQRLKNERHEEAELERLK
Receptor-Ligand Complex Structure
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PDB1i5k Structure and binding determinants of the recombinant kringle-2 domain of human plasminogen to an internal peptide from a group A Streptococcal surface protein.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		Y135 K139 F140 P153 D154 D156 W160 R169 W170 Y172
Binding residue
(residue number reindexed from 1)		Y37 K41 F42 P55 D56 D58 W62 R71 W72 Y74
Enzymatic activity
Enzyme Commision number 3.4.21.7: plasmin.
External links
PDB RCSB:1i5k, PDBe:1i5k, PDBj:1i5k
PDBsum1i5k
PubMed11350170
UniProtP00747|PLMN_HUMAN Plasminogen (Gene Name=PLG)

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