Structure of PDB 1hcq Chain B Binding Site BS02
Receptor Information
>1hcq Chain B (length=71) Species:
9606
(Homo sapiens) [
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TRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDK
NRRKSCQACRLRKCYEVGMMK
Ligand information
>1hcq Chain D (length=18) [
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ccaggtcactgtgacctg
Receptor-Ligand Complex Structure
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PDB
1hcq
The crystal structure of the estrogen receptor DNA-binding domain bound to DNA: how receptors discriminate between their response elements.
Resolution
2.4 Å
Binding residue
(original residue number in PDB)
G16 Y17 H18 Y19 K28 K32
Binding residue
(residue number reindexed from 1)
G13 Y14 H15 Y16 K25 K29
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003700
DNA-binding transcription factor activity
GO:0008270
zinc ion binding
GO:0043565
sequence-specific DNA binding
Biological Process
GO:0006355
regulation of DNA-templated transcription
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Molecular Function
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Biological Process
External links
PDB
RCSB:1hcq
,
PDBe:1hcq
,
PDBj:1hcq
PDBsum
1hcq
PubMed
8221895
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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