Structure of PDB 1h9t Chain B Binding Site BS02

Receptor Information
>1h9t Chain B (length=226) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AQSPAGFAEEYIIESIWNNRFPPGTILPAERELSELIGVTRTTLREVLQR
LARDGWLTIQHGKPTKVNNFWETSGLNILETLARLDHESVPQLIDNLLSV
RTNISTIFIRTAFRQHPDKAQEVLATANEVADHADAFAELDYNIFRGLAF
ASGNPIYGLILNGMKGLYTRIGRHYFANPEARSLALGFYHKLSALCSEGA
HDQVYETVRRYGHESGEIWHRMQKNL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1h9t The Structural Basis of Acyl Coenzyme A-Dependent Regulation of the Transcription Factor Fadr
Resolution3.25 Å
Binding residue
(original residue number in PDB)		S7 P8 A9 V43 T44 T46 T47 H65 G66
Binding residue
(residue number reindexed from 1)		S3 P4 A5 V39 T40 T42 T43 H61 G62
Binding affinityPDBbind-CN: Kd=0.2nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000062 fatty-acyl-CoA binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0042803 protein homodimerization activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006631 fatty acid metabolic process
GO:0019217 regulation of fatty acid metabolic process
GO:0045723 positive regulation of fatty acid biosynthetic process
GO:0045892 negative regulation of DNA-templated transcription
GO:0045893 positive regulation of DNA-templated transcription
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1h9t, PDBe:1h9t, PDBj:1h9t
PDBsum1h9t
PubMed11296236
UniProtP0A8V6|FADR_ECOLI Fatty acid metabolism regulator protein (Gene Name=fadR)

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