Structure of PDB 1h8a Chain B Binding Site BS02
Receptor Information
>1h8a Chain B (length=67) Species:
9606
(Homo sapiens) [
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DKHSDEYKIRRERNNIAVRKSRDKAKMRNLETQHKVLELTAENERLQKKV
EQLSRELSTLRNLFKQL
Ligand information
>1h8a Chain E (length=26) [
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ccagtccgttaaggattgcgccacat
Receptor-Ligand Complex Structure
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PDB
1h8a
Mechanism of C-Myb-C/Ebpbeta Cooperation from Separated Sites on a Promoter
Resolution
2.23 Å
Binding residue
(original residue number in PDB)
K269 Y274 R278 N282 R289
Binding residue
(residue number reindexed from 1)
K2 Y7 R11 N15 R22
Binding affinity
PDBbind-CN
: Kd=25.4nM
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003700
DNA-binding transcription factor activity
Biological Process
GO:0006351
DNA-templated transcription
GO:0006355
regulation of DNA-templated transcription
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Molecular Function
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Biological Process
External links
PDB
RCSB:1h8a
,
PDBe:1h8a
,
PDBj:1h8a
PDBsum
1h8a
PubMed
11792321
UniProt
P17676
|CEBPB_HUMAN CCAAT/enhancer-binding protein beta (Gene Name=CEBPB)
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