Structure of PDB 1h41 Chain B Binding Site BS02

Receptor Information
>1h41 Chain B (length=701) Species: 155077 (Cellvibrio japonicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EDGYDMWLRYQPIADQTLLKTYQKQIRHLHVAGDSPTINAAAAELQRGLS
GLLNKPIVARDEKLKDYSLVIGTPDNSPLIASLNLGERLQALGAEGYLLE
QTRINKRHVVIVAANSDVGVLYGSFHLLRLIQTQHALEKLSLSSAPRLQH
RVVNHWDNLNRVVERGYAGLSLWDWGSLPNYLAPRYTDYARINASLGING
TVINNVNADPRVLSDQFLQKIAALADAFRPYGIKMYLSINFNSPRAFGDV
DTADPLDPRVQQWWKTRAQKIYSYIPDFGGFLVKADSAGQPGPQGYGRDH
AEGANMLAAALKPFGGVVFWRAEDRFRGAYDEFMPLDGKFADNVILQIKN
GPIDFQPREPFSALFAGMSRTNMMMEFQITQEYFGFATHLAYQGPLFEES
LKTETHARGEGSTIGNILEGKVFKTRHTGMAGVINPGTDRNWTGHPFVQS
SWYAFGRMAWDHQISAATAADEWLRMTFSNQPAFIEPVKQMMLVSREAGV
NYRSPLGLTHLYSQGDHYGPAPWTDDLPRADWTAVYYHRASKTGIGFNRT
KTGSNALAQYPEPIAKAWGDLNSVPEDLILWFHHLSWDHRMQSGRNLWQE
LVHKYYQGVEQVRAMQRTWDQQEAYVDAARFAQVKALLQVQEREAVRWRN
SCVLYFQSVAGRPIPANYEQPEHDLEYYKMLARTTYVPEPWHPASSSRVL
K
Ligand information
Ligand IDCO
InChIInChI=1S/Co/q+2
InChIKeyXLJKHNWPARRRJB-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Co+2]
CACTVS 3.341[Co++]
FormulaCo
NameCOBALT (II) ION
ChEMBL
DrugBankDB14205
ZINC
PDB chain1h41 Chain B Residue 1728 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1h41 The Alpha-Glucuronidase,Glca67A,of Cellvibrio Japonicus Utilizes the Carboxylate and Methyl Groups of Aldobiouronic Acid as Important Substrate Recognition Determinants
Resolution1.5 Å
Binding residue
(original residue number in PDB)		M502 A625 M626 T629
Binding residue
(residue number reindexed from 1)		M491 A614 M615 T618
Annotation score1
Enzymatic activity
Enzyme Commision number 3.2.1.131: xylan alpha-1,2-glucuronosidase.
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0033939 xylan alpha-1,2-glucuronosidase activity
GO:0046559 alpha-glucuronidase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0045493 xylan catabolic process
GO:2000886 glucuronoxylan catabolic process
Cellular Component
GO:0005576 extracellular region
GO:0009279 cell outer membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1h41, PDBe:1h41, PDBj:1h41
PDBsum1h41
PubMed12654910
UniProtB3PC73|AGUA_CELJU Extracellular xylan exo-alpha-(1->2)-glucuronosidase (Gene Name=gla67A)

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