Structure of PDB 1ewq Chain B Binding Site BS02

Receptor Information
>1ewq Chain B (length=749) Species: 271 (Thermus aquaticus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MEGMLKGEGPGPLPPLLQQYVELRDQYPDYLLLFQVGDFYECFGEDAERL
ARALGLVLTHKTSKDFTTPMAGIPLRAFEAYAERLLKMGFRLAVADQVEP
VRREVTQLLTPGTLLQESLLPREANYLAAIATGDGWGLAFLDVSTGEFKG
TVLKSKSALYDELFRHRPAEVLLAPELLENGAFLDEFRKRFPVMLSEAPF
EPEGEGPLALRRARGALLAYAQRTQGGALSLQPFRFYDPGAFMRLPEATL
RALEVFEPLRGQDTLFSVLDETRTAPGRRLLQSWLRHPLLDRGPLEARLD
RVEGFVREGALREGVRRLLYRLADLERLATRLELGRASPKDLGALRRSLQ
ILPELRALLGEEVGLPDLSPLKEELEAALVEDPPLKVSEGGLIREGYDPD
LDALRAAHREGVAYFLELEERERERTGIPTLKVGYNAVFGYYLEVTRPYY
ERVPKEYRPVQTLKDRQRYTLPEMKEKEREVYRLEALIRRREEEVFLEVR
ERAKRQAEALREAARILAELDVYAALAEVAVRYGYVRPRFGDRLQIRAGR
HPVVERRTEFVPNDLEMAHELVLITGPNMAGKSTFLRQTALIALLAQVGS
FVPAEEAHLPLFDGIYTRIGAGKSTFMVEMEEVALILKEATENSLVLLDE
VGRGTSSLDGVAIATAVAEALHERRAYTLFATHYFELTALGLPRLKNLHV
AAREEAGGLVFYHQVLPGPASKSYGVEVAAMAGLPKEVVARARALLQAM
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1ewq Crystal structures of mismatch repair protein MutS and its complex with a substrate DNA.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		P1015 L1016 K1064 V1108 R1110 L1470 K1471 R1475
Binding residue
(residue number reindexed from 1)		P15 L16 K64 V101 R103 L463 K464 R468
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003684 damaged DNA binding
GO:0003690 double-stranded DNA binding
GO:0005524 ATP binding
GO:0030983 mismatched DNA binding
GO:0140664 ATP-dependent DNA damage sensor activity
Biological Process
GO:0006281 DNA repair
GO:0006298 mismatch repair

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Molecular Function
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Biological Process
External links
PDB RCSB:1ewq, PDBe:1ewq, PDBj:1ewq
PDBsum1ewq
PubMed11048710
UniProtQ56215|MUTS_THEAQ DNA mismatch repair protein MutS (Gene Name=mutS)

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