Structure of PDB 1eon Chain B Binding Site BS02

Receptor Information
>1eon Chain B (length=234) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLRSDLINALYDENQKYDVCGIISAEGKIYPLGSDTKVLSTIFELFSRPI
INKIAEKHGYIVEEPKQQNHYPDFTLYKPSEPNKKIAIDIKTTYTNKIKF
TLGGYTSFIRNNTKNIVYPFDQYIAHWIIGYVYTRVSLKTYNINELNEIP
KPYKGVKVFLQDKWVIAGDLAGSGNTTNIGSIHAHYKDFVEGKGIFDSED
EFLDYWRNYERTSQLRNKYNNISEYRNWIYRGRK
Ligand information
Receptor-Ligand Complex Structure
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PDB1eon Inhibition of EcoRV Endonuclease by Deoxyribo-3'-S-phosphorothiolates: A High-Resolution X-ray Crystallographic Study
Resolution1.6 Å
Binding residue
(original residue number in PDB)		T37 N70 K92 T93 T94 Y95 T106 T111 S112 K119 N120 S183 T186 N188
Binding residue
(residue number reindexed from 1)		T36 N69 K91 T92 T93 Y94 T101 T106 S107 K114 N115 S173 T176 N178
Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function
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Biological Process
External links
PDB RCSB:1eon, PDBe:1eon, PDBj:1eon
PDBsum1eon
PubMed
UniProtP04390|T2E5_ECOLX Type II restriction enzyme EcoRV (Gene Name=ecoRVR)

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