Structure of PDB 1ekb Chain B Binding Site BS02

Receptor Information
>1ekb Chain B (length=235) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IVGGSDSREGAWPWVVALYFDDQQVCGASLVSRDWLVSAAHCVYGRNMEP
SKWKAVLGLHMASNLTSPQIETRLIDQIVINPHYNKRRKNNDIAMMHLEM
KVNYTDYIQPICLPEENQVFPPGRICSIAGWGALIYQGSTADVLQEADVP
LLSNEKCQQQMPEYNITENMVCAGYEAGGVDSCQGDSGGPLMCQENNRWL
LAGVTSFGYQCALPNRPGVYARVPRFTEWIQSFLH
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1ekb Crystal structure of enteropeptidase light chain complexed with an analog of the trypsinogen activation peptide.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		H57 K99 Y174 D189 S190 S195 S214 F215 G216
Binding residue
(residue number reindexed from 1)		H41 K89 Y164 D181 S182 S187 S206 F207 G208
Enzymatic activity
Catalytic site (original residue number in PDB) H57 D102 Q192 G193 D194 S195 G196
Catalytic site (residue number reindexed from 1) H41 D92 Q184 G185 D186 S187 G188
Enzyme Commision number 3.4.21.9: enteropeptidase.
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1ekb, PDBe:1ekb, PDBj:1ekb
PDBsum1ekb
PubMed10493881
UniProtP98072|ENTK_BOVIN Enteropeptidase (Gene Name=TMPRSS15)

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