Structure of PDB 1ee4 Chain B Binding Site BS02
Receptor Information
>1ee4 Chain B (length=423) Species:
4932
(Saccharomyces cerevisiae) [
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QELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLV
EFMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGS
VEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTAT
WTLSNLCRGKKPQPDWSVVSQALPTLAKLIYSMDTETLVDACWAISYLSD
GPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQV
VINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIP
PLVKLLEVAEDKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDL
LEIADNRIIEVTLDALENILKMGEADKEARGLNINENADFIEKAGGMEKI
FNCQQNENDKIYEKAYKIIETYF
Ligand information
>1ee4 Chain F (length=4) Species:
9606
(Homo sapiens) [
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KRVK
Receptor-Ligand Complex Structure
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PDB
1ee4
Crystallographic analysis of the specific yet versatile recognition of distinct nuclear localization signals by karyopherin alpha.
Resolution
2.1 Å
Binding residue
(original residue number in PDB)
V327 T328 G329 W363 S366 N367 E402 W405
Binding residue
(residue number reindexed from 1)
V241 T242 G243 W277 S280 N281 E316 W319
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:1ee4
,
PDBe:1ee4
,
PDBj:1ee4
PDBsum
1ee4
PubMed
10745017
UniProt
Q02821
|IMA1_YEAST Importin subunit alpha (Gene Name=SRP1)
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