Structure of PDB 1dth Chain B Binding Site BS02
Receptor Information
>1dth Chain B (length=202) Species:
8730
(Crotalus atrox) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
QNLPQRYIELVVVADHRVFMKYNSDLNTIRTRVHEIVNFINGFYRSLNIH
VSLTDLEIWSNEDQINIQSASSDTLNAFAEWRETDLLNRKSHDNAQLLTA
IELDEETLGLAPLGTMCDPKLSIGIVQDHSPINLLMGVTMAHELGHNLGM
EHDGKDCLRGASLCIMRPGLTKGRSYEFSDDSMHYYERFLKQYKPQCILN
KP
Ligand information
Ligand ID
CA
InChI
InChI=1S/Ca/q+2
InChIKey
BHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
Software
SMILES
CACTVS 3.341
[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Ca+2]
Formula
Ca
Name
CALCIUM ION
ChEMBL
DrugBank
DB14577
ZINC
PDB chain
1dth Chain B Residue 904 [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
1dth
Batimastat, a potent matrix mealloproteinase inhibitor, exhibits an unexpected mode of binding.
Resolution
2.0 Å
Binding residue
(original residue number in PDB)
E9 D93 C197 N200
Binding residue
(residue number reindexed from 1)
E9 D93 C197 N200
Annotation score
4
Enzymatic activity
Enzyme Commision number
3.4.24.42
: atrolysin C.
Gene Ontology
Molecular Function
GO:0004222
metalloendopeptidase activity
GO:0008237
metallopeptidase activity
Biological Process
GO:0006508
proteolysis
View graph for
Molecular Function
View graph for
Biological Process
External links
PDB
RCSB:1dth
,
PDBe:1dth
,
PDBj:1dth
PDBsum
1dth
PubMed
8610113
UniProt
P15167
|VM1AD_CROAT Snake venom metalloproteinase atrolysin-D
[
Back to BioLiP
]