Structure of PDB 1c3x Chain B Binding Site BS02
Receptor Information
>1c3x Chain B (length=266) Species:
40001
(Cellulomonas sp.) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
PPLDDPATDPFLVARAAADHIAQATGVEGHDMALVLGSGWGGAAELLGEV
VAEVPTHEIPGFSSVTRSIRVERADGSVRHALVLGSRTHLYEGKGVRAVV
HGVRTAAATGAETLILTNGCGGLNQEWGAGTPVLLSDHINLTARSPLEGP
TFVDLTDVYSPRLRELAHRVDPTLPEGVYAQFPGPHYETPAEVRMAGILG
ADLVGMSTTLEAIAARHCGLEVLGVSLVTNLAAGISPTPLSHAEVIEAGQ
AAGPRISALLADIAKR
Ligand information
Ligand ID
CA
InChI
InChI=1S/Ca/q+2
InChIKey
BHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
Software
SMILES
CACTVS 3.341
[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Ca+2]
Formula
Ca
Name
CALCIUM ION
ChEMBL
DrugBank
DB14577
ZINC
PDB chain
1c3x Chain B Residue 300 [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
1c3x
Crystal structure of the purine nucleoside phosphorylase (PNP) from Cellulomonas sp. and its implication for the mechanism of trimeric PNPs.
Resolution
2.4 Å
Binding residue
(original residue number in PDB)
G126 E128
Binding residue
(residue number reindexed from 1)
G110 E112
Annotation score
1
Enzymatic activity
Catalytic site (original residue number in PDB)
S46 R83 H105 Y107 E108 G135 M222 S223 N246 H258
Catalytic site (residue number reindexed from 1)
S38 R67 H89 Y91 E92 G119 M206 S207 N230 H242
Enzyme Commision number
2.4.2.1
: purine-nucleoside phosphorylase.
Gene Ontology
Molecular Function
GO:0003824
catalytic activity
GO:0004731
purine-nucleoside phosphorylase activity
GO:0016757
glycosyltransferase activity
GO:0016763
pentosyltransferase activity
Biological Process
GO:0006139
nucleobase-containing compound metabolic process
GO:0009116
nucleoside metabolic process
Cellular Component
GO:0005737
cytoplasm
View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB
RCSB:1c3x
,
PDBe:1c3x
,
PDBj:1c3x
PDBsum
1c3x
PubMed
10600382
UniProt
P81989
|PUNA_CELSP Purine nucleoside phosphorylase (Gene Name=punA)
[
Back to BioLiP
]