Structure of PDB 1aph Chain B Binding Site BS02

Receptor Information
>1aph Chain B (length=30) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FVNQHLCGSHLVEALYLVCGERGFFYTPKA
Ligand information
Ligand IDDCE
InChIInChI=1S/C2H4Cl2/c3-1-2-4/h1-2H2
InChIKeyWSLDOOZREJYCGB-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341		ClCCCl
OpenEye OEToolkits 1.5.0C(CCl)Cl
FormulaC2 H4 Cl2
Name1,2-DICHLOROETHANE;
ETHYLENE DICHLORIDE
ChEMBLCHEMBL16370
DrugBankDB03733
ZINCZINC000008220695
PDB chain1aph Chain B Residue 200 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1aph Conformational changes in cubic insulin crystals in the pH range 7-11.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		S9 E13
Binding residue
(residue number reindexed from 1)		S9 E13
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:1aph, PDBe:1aph, PDBj:1aph
PDBsum1aph
PubMed1477273
UniProtP01317|INS_BOVIN Insulin (Gene Name=INS)

[Back to BioLiP]