Structure of PDB 1a3q Chain B Binding Site BS02

Receptor Information
>1a3q Chain B (length=285) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPYLVIVEQPKQRGFRFRYGCEGPSHGGLPGASSEKGRKTYPTVKICNYE
GPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGICAVSVGPKDMTAQFNNL
GVLHVTKKNMMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKELKKVMD
LSIVRLRFSAFLRSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSVRG
GDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVHKQYAIVFRTP
PYHKMKIERPVTVFLQLKRKRGGDVSDSKQFTYYP
Ligand information
Receptor-Ligand Complex Structure
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PDB1a3q Structure of the human NF-kappaB p52 homodimer-DNA complex at 2.1 A resolution.
Resolution2.1 Å
Binding residue
(original residue number in PDB)
Y55 C57 E58 K143 P223 Q254 Q284
Binding residue
(residue number reindexed from 1)
Y19 C21 E22 K107 P181 Q212 Q242
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005737 cytoplasm

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:1a3q, PDBe:1a3q, PDBj:1a3q
PDBsum1a3q
PubMed9384586
UniProtQ00653|NFKB2_HUMAN Nuclear factor NF-kappa-B p100 subunit (Gene Name=NFKB2)

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