Structure of PDB 1a3q Chain B Binding Site BS02
Receptor Information
>1a3q Chain B (length=285) Species:
9606
(Homo sapiens) [
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GPYLVIVEQPKQRGFRFRYGCEGPSHGGLPGASSEKGRKTYPTVKICNYE
GPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGICAVSVGPKDMTAQFNNL
GVLHVTKKNMMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKELKKVMD
LSIVRLRFSAFLRSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSVRG
GDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVHKQYAIVFRTP
PYHKMKIERPVTVFLQLKRKRGGDVSDSKQFTYYP
Ligand information
>1a3q Chain D (length=11) [
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ggggattcccc
Receptor-Ligand Complex Structure
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PDB
1a3q
Structure of the human NF-kappaB p52 homodimer-DNA complex at 2.1 A resolution.
Resolution
2.1 Å
Binding residue
(original residue number in PDB)
Y55 C57 E58 K143 P223 Q254 Q284
Binding residue
(residue number reindexed from 1)
Y19 C21 E22 K107 P181 Q212 Q242
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003677
DNA binding
GO:0003700
DNA-binding transcription factor activity
Biological Process
GO:0006355
regulation of DNA-templated transcription
Cellular Component
GO:0005737
cytoplasm
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External links
PDB
RCSB:1a3q
,
PDBe:1a3q
,
PDBj:1a3q
PDBsum
1a3q
PubMed
9384586
UniProt
Q00653
|NFKB2_HUMAN Nuclear factor NF-kappa-B p100 subunit (Gene Name=NFKB2)
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