Structure of PDB 1a1a Chain B Binding Site BS02
Receptor Information
>1a1a Chain B (length=102) Species:
9606
(Homo sapiens) [
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AEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYSLSVSDFDNA
KGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTV
CP
Ligand information
>1a1a Chain D (length=3) [
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YEc
Receptor-Ligand Complex Structure
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PDB
1a1a
Peptide ligands of pp60(c-src) SH2 domains: a thermodynamic and structural study.
Resolution
2.0 Å
Binding residue
(original residue number in PDB)
R158 R178 T182 S188 K203 H204 Y205 G239
Binding residue
(residue number reindexed from 1)
R11 R31 T35 S41 K56 H57 Y58 G92
Enzymatic activity
Enzyme Commision number
2.7.10.2
: non-specific protein-tyrosine kinase.
External links
PDB
RCSB:1a1a
,
PDBe:1a1a
,
PDBj:1a1a
PDBsum
1a1a
PubMed
9174343
UniProt
P12931
|SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src (Gene Name=SRC)
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