Structure of PDB 6z1p Chain Ax Binding Site BS02

Receptor Information

>6z1p Chain Ax (length=132) Species: 312017 (Tetrahymena thermophila SB210)

RLPKNLNILKDPKAFKNYCLNPLGLTQKTSNFPKEQKVEKFCNWEMVVHR
GEKPLENNTVVLKCDPKLAKPEIKQYLTKLYGLELNKVNTVRYTGKLKNS
ILRKTFKTKDFKKVYAVLKTEVEPFYQKIETM

Ligand information

>6z1p Chain Ab (length=2237)

uaguaaauuucaauaaguuuuugaaauugaaaaauagagaucuaccucua
aaacuuguaaaguuuaaauucaauagaaaacaguaccgcgagggaaaggu
gaaaagauuuuauaauaucuuaaaagaaccugaaauuuagugcuaaauac
aguuaaagcuuuauuguuuuaacguaccuuuugcauaaugggcuagcgag
uuuauauaauuagcgaguaauuuaaauuuuauaaaauuacgaaucgauag
aauaaauaguuaauuauauaagacccgaagcuaagugaucuaauuaugau
uagauuaaggguauuuauaccugaggaucgaacucuuaaauguugcaaaa
uuuugggauaaauuguaauuaggggugaaaggcuuaucaaacuuaguuau
agcugguuuuccacgaaaccuauuuaaguaggguguuauuuuuuauaaua
auuagguuuaaauaacuauaucuauaauuaauuuguuaauuauaaaauua
guauauaauaauuaguuauuauuagauaauaaccagacuauuagcgcuaa
gguuuauagucaagagagaaacagcucagauuaaacaauaaggucuuuaa
aaauaaauaauuauggagauuauuuuuguuaauacuaauaagauguaggc
uuggaagcagccaucauuuuaaaaaagcguaaaagcuuaauauuagauaa
auuaauguuaaaaauuaauugauacuuaaauaaucauagaugaagagaga
auaauuuuuauuuaccgaauugauaaaucgaaagaugguaguggaacguu
uuguauaaaaaaauaaaauugugaaauuuuauauuuuaucaauauugaua
augcuagcaugaguaguagacauaaugugagaaucauuaucgccugauau
acaaggguuacuaaauuugauaaucuuauuuaguguaagucgauuucuaa
gauauaaaaguauauuguuaucaaugaauauaaaauauaaaauaucuaau
aaacuacuuuuuauauuauauaaaauuuuuuauaauauaggugguuuagu
gacuggaaauguuuauauuuuauuaaaucguacuaacucuaacacaagug
uuuaaguagaauauauaauggcgaaggaguaaaaaguauugaaggaacua
ggcaaaauaacccuguaacuuugggagaaagggggcuuuuaagcaacuga
aaagagagaguagcgacuguuuaauaaaaacauaagauuuugcaaaauuu
aaauaugauguauaaaaucugacaccugcccggugcugcaaggugaaucu
auuuuaguuaacgcugaaauauuaaaccccaguaaacggcggccguaacc
cugacgguccuaagguagcaaaauuccuuggcggguaaguuccguccugc
augaaugguguaacgacugcucugcugucuccaauacuugcucuacgaaa
uugaacuuuccgugaagaugcggcaauauuacaacuagacgggaagaccc
uaugcaccuuuacuguuaucuguaauuaauuuaauuacauauaaauaaaa
uaaauuuuaauuauuuuuguuauugaaagacaguuugacuggggcggucu
ccuccuaaaaaguaacggaggaguauaauaauuugggguaucuuauuuua
auugagaucaauauuagaaugaauauacuaaauuugauuagaguacaaac
aaguauucuaaggauauaugucugucauauugacccgauauaauuuagua
gaaaauauaucgaucaacgaauaaaagguacgcuagggauaacaggcuua
uggguuuugagaguucuuauuaauaaacccguuuggcaccucgaugucgg
cucaucacauccugaugguggacaaucuaucaaggguccggcuguucgcc
gguuaaagugguacgugagcuggguuuaaaacgucgugagacaguuuggu
cccuaucuguuguaauuacaagaaaauaaauaagaauuaacuuuaguacg
agaggacuaggaaaauuuaaucacugguuugaaaauuacuuuaauaaaua
aaaguacgguuuuuaagcuaaauuaaacaagauaauugcugaauucuaua
uaagcaagaaucuaacuuauauuauuuucuaauaaacuuuuuaaagacua
uauuauuuaaguauauuuauuaagagucauuauaacuaauaaauauaaau
auacuaaauguuuaauaaucacuacaguuuaguuuuu

.....<<<<<<<<.......>>>>>>>>......<<<<<..((((>>>>>
...................................<<....>>.......
..................................................
.<<<<<<<<......>>>>>>>>...<.<........>.>.<<<<<<...
.<<<<<<<<<<<<...<<<..................>>>...<<....>
>........>>>>>>>>>>>>..<<.<...<<<<<<.....<<<<<<<<<
..<<<...<<<<<<..>>>>>>....>>>...<<<..<<<<........>
>>>.>>>....>>>>>>>>>...<<<.....>>>......>>>>>>....
..>.>>..<<<<<<....<<<<<....>>>>><<<<<<<<....<<<<<<
<<<.....<..<<.<<<<..<..<<<<<<<<....>>>>>>>>..>..>>
>>..>>.>.....>>>>>>>>>..>>>>>>.>>..<<<<<<.<<<.....
.>>>.>>>>>>....<<<......>>>...<<<..<<<...<<<(((...
<<<<<<<..........<<<<<<<<....<<...<<<<<<..<<<..<<<
<.......>>>>..>>>.......<<<<......>>>>..>>>>>>...<
<<<<...........>>>>>..>>...>>>>>>>>...........))).
......>>>>>>>>>>...>>>.>>><<<....>>>....>>>>>><<..
<<<...<<....<<<<<<<<....>>>>>>>>...>>..>>>...>>...
..>>>>>><......<<....<<<<<<.......>>>>>><<<<....<.
<<..<....<<<<<<.............>>>>>>.......<<<.<<...
<<<....<<.....>>...>>>...>>....<<<<<<<<<<...<<...<
<<<<<<<.....<<<<<<<<....[[.[[.>>>>>>>>..>>>>>>>>..
>>.........>>>>>>>>>>.....>>>....>....<<......>>.>
>.>..<<<.....>>>...>>>>..<<<<<...<<<<<<<..<<......
..........<<<<...............>>>>.<<......>>......
......<<<<<<<<<..<<<.........>>>..<<<<<<<.....<<..
....>>.......>>>>>>>.<<<<<.<<<..<<<<<<...<<<.....<
<<<<<<<<....>>>>>>>>>....>>>.>>>>..>>>>><<<<<<....
...>>>>>>........<...........<<<<<.......>>>>>....
.>....>>>>>..>>.>>>>>>>.....>>..>>>>>>>>>>>>>>....
.>.....<.<<<........>>>.>..<<<<<<<<.<<<.<<<.....<<
<<.<.<<<<..<<<<...<<.<<<<<<<<<<.>>>>>.<.<<<<......
..........>>>>.>..>>>>>.>>....>>>>..<<<<.....>>>><
<<<<<...........>>>>>>..<<...<<<<<<<...<<<<<<.....
..>>>>>>....<<<...(((>>>...>>>>>>>...<<<<<<<<<....
..>>>>>>>>>.<<<....>>>.>>))).......<<<<<<.<<<..)))
)..>>>>>>>>>.............>>>>...>>>>>.......<<<<..
.<<<<<<...<<.......>>...>>>>>>....>>>.>.......<.<<
<.<<<<<<..<<<<<<<<........>>>>>>..>>.<<<<<.....>>>
>>.....>>>>>..>...>>>..>....<<<<<<<....>>>.>>>>...
>>>..>>>>>>>>>>>....<<<<<<<<.<<<<<.<<<..<<<.......
........>>>..>>><<<<<....<<<..<<<<<<<<<<<<...]]]].
>>>>>>..>>>>>>..>>>..>>>>>...<<<...<<<<<..........
..>>>>>...>>>..>>>>>..>>>>>>>>...<<<<.<..<<.......
>>..>....<<<<<<<<<<<.........<.......>......>>>>>>
>>>>>....>>>>........................

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6z1p Ciliate mitoribosome illuminates evolutionary steps of mitochondrial translation.
• Resolution: 3.7 Å
• Binding residue (original residue number in PDB): H55 E58 K59 K76 N95 T96 V97 R98 Y99 K104 K110 K118 K119 Y121
• Binding residue (residue number reindexed from 1): H49 E52 K53 K70 N89 T90 V91 R92 Y93 K98 K104 K112 K113 Y115

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0006412 translation
• GO:0032543 mitochondrial translation

Cellular Component

• GO:0005739 mitochondrion
• GO:0005762 mitochondrial large ribosomal subunit
• GO:0005840 ribosome
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:6z1p, PDBe:6z1p, PDBj:6z1p
• PDBsum: 6z1p
• PubMed: 32553108
• UniProt: Q22EY1