Structure of PDB 8q87 Chain Am Binding Site BS02

Receptor Information

>8q87 Chain Am (length=150) Species: 9031 (Gallus gallus)

GRMHAPGKGLSQSALPYRRSVPTWLKLTSDDVKEQIYKLAKKGLTPSQIG
VILRDSHGVAQVRFVTGNKILRILKSKGLAPDLPEDLYHLIKKAVAVRKH
LERNRKDKDAKFRLILIESRIHRLARYYKTKRVLPPNWKYESSTASALVA

Ligand information

>8q87 Chain A2 (length=1697)

uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucuaaguacacacgggcgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgcuccuacuuggauaacugugguaa
uucuagagcuaauacaugccgacgagcgccgaccuccggggacgcgugca
uuuaucaguggugacucuagauaaccucgagccgaucgcacgcccccgug
gcggcgacgacccauucgaaugucugcccuaucaacuuucgaugguacug
ucugugccuaccauggugaccacggguaacggggaaucaggguucgauuc
cggagagggagccugagaaacggcuaccacauccaaggaaggcagcaggc
gcgcaaauuacccacucccgacccggggagguagugacgaaaaauaacaa
uacaggacucuuucgaggcccuguaauuggaaugaguccacuuuaaaucc
uuuaacgaggauccauuggagggcaagucuggugccagcagccgcgguaa
uuccagcuccaauagcguauauuaaaguugcugcaguuaaaaagcucgua
guuggaucuugggaucgagcugccgccugucccaggucucucggcgcccc
ggggcccgaagcguuuacuuugaaaaaauuagaguguucaaagcaggcug
gccgccggaauacuccagcuaggaauaauggaauaggacuccgguucuau
uuuguugguuuucggaaacggggccaugauuaagagggacggccgggggc
auucguauugugccgcuagaggugaaauucuuggaccggcgcaagacgaa
cuaaagcgaaagcauuugccaagaauguuuucauuaaucaagaacgaaag
ucggagguucgaagacgaucagauaccgucguaguuccgaccauaaacga
ugccgacucgcgauccggcggcguuauucccaugacccgccgggcagcuc
ccgggaaacccaagucuuuggguuccggggggaguaugguugcaaagcug
aaacuuaaaggaauugacggaagggcaccaccaggaguggagccugcggc
uuaauuugacucaacacgggaaaccucacccggcccggacacggacagga
uugacagauugagagcucuuucucgauuccgugggugguggugcauggcc
guucuuaguugguggagcgauuugucugguuaauuccgauaacgaacgag
acucuggcaugcuaacuaguuacgcgacccccgagcggucggcguccaac
uucuuagagggacaaguggcguucagccacccgagauugagcaauaacag
gucugugaugcccuuagauguccggggcugcacgcgcgcuacacugacug
gcucagcuugugucuacccuacgccggcaggcgcggguaacccguugaac
cccauucgugauggggaucggggauugcaauuauuccccaugaacgagga
auucccaguaagugcgggucauaagcucgcguugauuaagucccugcccu
uuguacacaccgcccgucgcuacuaccgauuggaugguuuagugaggucc
ucggaucggccgucgagaagacggucgaacuugacuaucuagaggaagua
aaagucguaacaagguuuccguaggugaaccugcggaaggaucauua

...<<<<<.[.((((>>>>><<<.<<<<<<...<.<<..<......<<<.
<<<..<<....<<....<<..........>>...>>.>>......<<...
.....<<<.<<<..<<....<<<<<.........<<.....<<.<<<...
..>>>.>>......>>.........<<<<...<<<..>>>...>>>><<.
.<<<<<...<......>..>>>>>......>>...<<<<.<<<<.....>
>>>>>>>.>>.>>>...>>>>>.>>>.<<<....<<<....<<<<<<...
........>>>>>>>>>......>>>...<<<.<<<<....>>>>....>
>>.>>.<<.<<<..........>>>.>>.<.<<....>>.>...>>>>>>
.........<<<....<<<<...>>>>..>>>..>...>>.>.....<<<
<<<<<<.<<<....>>>..>>>>>>.>>>......<<..<..........
.>..>>.........<<<<<((....<.<<<<.....<<..))>>.....
..>>>>>>>>>>..>>>>>>.>>>.........<.<((.....<.<<...
<<<.<<.....<<..<<.<<....>>.>>..>>...<...<<<..<<<<<
>>>>>.>>>.>...<<<<<<.<.......<<...<.......>..<<<..
...>>>....>>......>.>>>..>>>........<.<<<<<.<<<<..
.............>>>>.>>>>>.>....>>....<<<<<<..<...<<<
<..<<..<<<<<<<<...<<<......>>>......>>>>>>>>..>>..
.....<<....>>...>>>>..>..>>>.>>>...>>>...>>.>....<
<<<<<<...<...<<<<.<.....>.>>>>...>>>>>>>>.........
.<<<.<<..<<..<<<<<<<<.<<<<<....>>>>>>>>>>>>>..>>..
..<<..))>>...>>.....>>>.>.>.<<<......<<<<....>>>>.
...>>>..)))).]<<<<<.<<<<<<<..<<..<<<<<..<<<.<<<<<.
......<<........>>..........<<<<<.<....<<<<<<.....
..<<.<<<........>>>.>>.....>>>>>>...<<.<<<..<<.<<<
<<<....<<<.<<<<<....>>>...<<<......>>>...>>.>>>...
.<<<...<...<<<<..<<<<<<<<<<<<.......>>>>.>>>>..>>>
>..>>>>..>.....<<<<<.....>>>>>........>>>....>>>.>
>>.....>>>>>>>.....>.>>>>>....>.>>>>.>>>.....<<.<<
<........<.......<<<.<<<<....>>>>.>>>....>........
.>>>.>>......<.....<<<<<..........>>>>>.....>.....
>>>>>.....<<<<<<<<.......>>>>>>>>......>>...>>>>>>
>>>>.>>....<..<<.<..<<<<.<<....<<<<<<<<.<<<..<<<<.
<<...<<<<...>>>>...>>.>>>>..>>>.>>>>>>>>...>>.>>>>
...>.>>...>.....<<<<<<<<<<..>>>>>>>>>>.........

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8q87 Structural insights into inactive ribosome complexes derived from cold-treated chick embryo cells
• Resolution: 2.4 Å
• Binding residue (original residue number in PDB): G2 R3 M4 H5 G8 K9 G10 L11 S12 Q13 S14 A15 L16 P17 R20 S48 G51 V52 R55 A61 Q62 R64 N69 K70 I71 L72 R73 D87 H90 K94 H101 R104 N105 R106 K107 D108 D110 K112 F113 R114 I116 L117 S120 R121 R124 R127 Y128
• Binding residue (residue number reindexed from 1): G1 R2 M3 H4 G7 K8 G9 L10 S11 Q12 S13 A14 L15 P16 R19 S47 G50 V51 R54 A60 Q61 R63 N68 K69 I70 L71 R72 D86 H89 K93 H100 R103 N104 R105 K106 D107 D109 K111 F112 R113 I115 L116 S119 R120 R123 R126 Y127

External links

• PDB: RCSB:8q87, PDBe:8q87, PDBj:8q87
• PDBsum: 8q87
• UniProt: Q6ITC7|RS13_CHICK Small ribosomal subunit protein uS15 (Gene Name=RPS13)