Structure of PDB 8ppl Chain Ae Binding Site BS02

Receptor Information
>8ppl Chain Ae (length=59) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KVHGSLARAGKVRGQTPKVAKQEKKKKKTGRAKRRMQYNRRFVNVVPTFG
KKKGPNANS
Ligand information
>8ppl Chain Aj (length=29) Species: 1335626 (Middle East respiratory syndrome-related coronavirus) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
TSCPEWMDDFEADPKGKYAQNLLKKLIGG
Receptor-Ligand Complex Structure
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PDB8ppl Universal features of Nsp1-mediated translational shutdown by coronaviruses.
Resolution2.65 Å
Binding residue
(original residue number in PDB)		F49 K51
Binding residue
(residue number reindexed from 1)		F49 K51
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0002227 innate immune response in mucosa
GO:0006412 translation
GO:0019731 antibacterial humoral response
GO:0050830 defense response to Gram-positive bacterium
GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide
Cellular Component
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022626 cytosolic ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8ppl, PDBe:8ppl, PDBj:8ppl
PDBsum8ppl
PubMed37802027
UniProtP62861|RS30_HUMAN Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein (Gene Name=FAU)

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