Structure of PDB 7o80 Chain Ae Binding Site BS02

Receptor Information
>7o80 Chain Ae (length=191) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TPDIKLFGKWSTDDVQINDISLQDYIAVKEKYAKYLPHSAGRYAAKRFRK
AQCPIVERLTNSMMMHGRNNGKKLMTVRIVKHAFEIIHLLTGENPLQVLV
NAIINSGPREDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREAAF
RNIKTIAECLADELINAAKGSSNSYAIKKKDELERVAKSNR
Ligand information
>7o80 Chain AI (length=76) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
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Receptor-Ligand Complex Structure
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PDB7o80 Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome.
Resolution2.9 Å
Binding residue
(original residue number in PDB)
R136 K192 E195 R198 S202
Binding residue
(residue number reindexed from 1)
R123 K179 E182 R185 S189
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0006412 translation
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022626 cytosolic ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Cellular Component
External links
PDB RCSB:7o80, PDBe:7o80, PDBj:7o80
PDBsum7o80
PubMed34029205
UniProtG1TFM5|RS5_RABIT Small ribosomal subunit protein uS7 (Gene Name=RPS5)

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