Structure of PDB 8cre Chain AZ Binding Site BS02

Receptor Information
>8cre Chain AZ (length=292) Species: 5476 (Candida albicans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MQKEFRTSAYHSRFQTPFRRRQEGKTDYYQRKRLVTQHKAKYNSPKYRLV
VRFTNKDIIAQIVSAHITGDVVFTAAYAHELPRYGIKYGLTNWSAAYAVG
LLVARRALQKLGLDETYTGVEEVEGEFELTEAVEDGPRPFKVFLDIGLQR
TTTGARVFGVLKGASDGGLYVPHSPNRFPGWDIEAEELDAELLRKYIFGG
HVAEYMEELLDDDEEKYKSIFKNYIEEEIESEDVEEIYANAHEAIRADPS
FKPTEKKFTKEQYKAESKKYRQQKLTRAERQAKVAKKIAEFK
Ligand information
>8cre Chain AT (length=121) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gguugcggccauaucuagcagaaagcaccguuccccguucgaucaaccgu
aguuaagcugcuaagagcaauaccgaguaguguagugggagaccauacgc
gaaacuauugugcugcaaucu
<<<<<<<<<....<<<<<<<<.....<<.<<<............>>>...
.>>....>>>>>>.>><<<<<<.......<<<<<..<<....>>.>>>>>
.....>>>>>>>>>>>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8cre Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement
Resolution3.0 Å
Binding residue
(original residue number in PDB)
S10 H13 S14 T18 F20 R21 R22 Q24 T28 Y30 R33 R50 V52 R54 T56 N57 K58 I69 T70 G71 D72 V73 V74 Y79 G91 N94 W95 R152 T154 T155 G156 A157 R158 Y198 H203 V204 Y207 K218 S221 I222 N225 Y226 F253 T256 F260 K262 Y265 K266 E268 S269 Y272 R273 Q274 K276 L277 R279 K285
Binding residue
(residue number reindexed from 1)
S8 H11 S12 T16 F18 R19 R20 Q22 T26 Y28 R31 R48 V50 R52 T54 N55 K56 I67 T68 G69 D70 V71 V72 Y77 G89 N92 W93 R150 T152 T153 G154 A155 R156 Y196 H201 V202 Y205 K216 S219 I220 N223 Y224 F251 T254 F258 K260 Y263 K264 E266 S267 Y270 R271 Q272 K274 L275 R277 K283
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