Structure of PDB 4v68 Chain AZ Binding Site BS02

Receptor Information
>4v68 Chain AZ (length=378) Species: 274 (Thermus thermophilus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GEFIRTKPHVNVGTIGHVDHGKTTLTAALTFVTAAENPAHVEYETAKRHY
SHVDCPGHADYIKNMITGAAQMDGAILVVSAADGPMPQTREHILLARQVG
VPYIVVFMNKVDMVDDPELLDLVEMEVRDLLNQYEFPGDEVPVIRGSALL
ALEQMHRNPKTRRGENEWVDKIWELLDAIDEYIPTPVRDVDKPFLMPVED
VFTITGRGTVATGRIERGKVKVGDEVEIVGLAPETRKTVVTGVEMHRKTL
QEGIAGDNVGVLLRGVSREEVERGQVLAKPGSITPHTKFEASVYVLKKEE
GGRHTGFFSGYRPQFYFRTTDVTGVVQLPPGVEMVMPGDNVTFTVELIKP
VALEEGLRFAIREGGRTVGAGVVTKILE
Ligand information
>4v68 Chain AY (length=72) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcggauuuagcucaggagagcgccagacugaagaucuggagguccugugu
ucgauccacagaauucgcacca
<<<<<<<..<<<<....>>>>.<<<<<.......>>>>>.....<<<<<.
......>>>>>>>>>>>>....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4v68 GTPase activation of elongation factor EF-Tu by the ribosome during decoding
Resolution6.4 Å
Binding residue
(original residue number in PDB)		D87 F229 T230 I231 R234 V237 E271 R274 G287 L289 R295 R330 T332 F335 Q341 T350 E390 G391 G392
Binding residue
(residue number reindexed from 1)		D60 F202 T203 I204 R207 V210 E244 R247 G260 L262 R268 R303 T305 F308 Q314 T323 E363 G364 G365
Enzymatic activity
Catalytic site (original residue number in PDB) K24 T25 H85
Catalytic site (residue number reindexed from 1) K22 T23 H58
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003746 translation elongation factor activity
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0006412 translation
GO:0006414 translational elongation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4v68, PDBe:4v68, PDBj:4v68
PDBsum4v68
PubMed19229291
UniProtP60339|EFTU2_THET8 Elongation factor Tu-B (Gene Name=tufB)

[Back to BioLiP]