Structure of PDB 4v5q Chain AZ Binding Site BS02

Receptor Information
>4v5q Chain AZ (length=385) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKGEFVRTKPHVNVGTIGHVDHGKTTLTAALTYVAAAENPNVINTAHVEY
ETAKRHYSHVDCPGHADYIKNMITGAAQMDGAILVVSAADGPMPQTREHI
LLARQVGVPYIVVFMNKVDMVDDPELLDLVEMEVRDLLNQYEFPGDEVPV
IRGSALLALEQMHRNPKTRRGENEWVDKIWELLDAIDEYIPTPVRDVDKP
FLMPVEDVFTITGRGTVATGRIERGKVKVGDEVEIVGLAPETRRTVVTGV
EMHRKTLQEGIAGDNVGVLLRGVSREEVERGQVLAKPGSITPHTKFEASV
YVLKKEEGGRHTGFFSGYRPQFYFRTTDVTGVVQLPPGVEMVMPGDNVTF
TVELIKPVALEEGLRFAIREGGRTVGAGVVTKILE
Ligand information
>4v5q Chain AY (length=77) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aggggcguaguucaauugguagaacaccggucuccaaaaccggguguugg
gaguucgagucucuccgccccugccaW
<<<<<<<..<<<..........>>>.<<<<<.......>>>>>.....<<
<<<.......>>>>>>>>>>>>.....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4v5q How Mutations in tRNA Distant from the Anticodon Affect the Fidelity of Decoding.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		H67 Y88 K90 F229 T230 I231 T232 R234 V237 T239 E271 H273 R274 N285 G287 R295 R330 T332 G337 Y338 R339 Q341 T350 G391
Binding residue
(residue number reindexed from 1)		H47 Y68 K70 F209 T210 I211 T212 R214 V217 T219 E251 H253 R254 N265 G267 R275 R310 T312 G317 Y318 R319 Q321 T330 G371
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003746 translation elongation factor activity
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0006412 translation
GO:0006414 translational elongation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4v5q, PDBe:4v5q, PDBj:4v5q
PDBsum4v5q
PubMed21378964
UniProtQ5SHN6|EFTU1_THET8 Elongation factor Tu-A (Gene Name=tufA)

[Back to BioLiP]