Structure of PDB 6c5l Chain AY Binding Site BS02

Receptor Information
>6c5l Chain AY (length=351) Species: 274 (Thermus thermophilus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LAQRLEGLRGYLDIPQKETRLKELERRLEDPSLWNDPEAARKVSQEAARL
RRTVDTFRSLESDLQGLLELMEELPAEEREALKPELEEAAKKLDELYHQT
LLNFPHAEKNAILTIQPGAGGTEACDWAEMLLRMYTRFAERQGFQVEVVD
LTPGPEAGIDYAQILVKGENAYGLLSPEAGVHRLVRPSPFDASGRRHTSF
AGVEVIPEVDEEVEVVLKPEELRIDVMRASGPGGQGVNTTDSAVRVVHLP
TGITVTCQTTRSQIKNKELALKILKARLYELERKKREEELKALRGEVRPI
EWGSQIRSYVLDKNYVKDHRTGLMRHDPENVLDGDLMDLIWAGLEWKAGR
R
Ligand information
>6c5l Chain AV (length=76) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcccggauagcucagucgguagagcaggggauugaaaauccccguguccu
ugguucgauuccgaguccgggcacca
.<<<<<<..<<<<........>>>><<<<<<<.....>>>>>>.>...<<
<<<.......>>>>>>>>>>>.....
Receptor-Ligand Complex Structure
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PDB6c5l Conformation of methylated GGQ in the Peptidyl Transferase Center during Translation Termination.
Resolution3.2 Å
Binding residue
(original residue number in PDB)
E161 G238 R266 K270
Binding residue
(residue number reindexed from 1)
E156 G233 R261 K265
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003747 translation release factor activity
GO:0016149 translation release factor activity, codon specific
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
GO:0006415 translational termination
Cellular Component
GO:0005737 cytoplasm

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6c5l, PDBe:6c5l, PDBj:6c5l
PDBsum6c5l
PubMed29403017
UniProtQ5SM01|RF2_THET8 Peptide chain release factor RF2 (Gene Name=prfB)

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